tag:blogger.com,1999:blog-15575652.post5674319658066763186..comments2024-03-05T00:59:35.390+08:00Comments on Angry Doctor: To write is to sit in judgement on oneselfangry dochttp://www.blogger.com/profile/03132410467147982699noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-15575652.post-58765953802050573012013-01-04T15:07:58.239+08:002013-01-04T15:07:58.239+08:00Pretty effective material, much thanks for your ar...Pretty effective material, much thanks for your article.<br /><a href="http://noemikawa.tumblr.com" rel="nofollow">superb 3</a> | <a href="http://spearenevgee1974.posterous.com/business-lead-a-pleasant-sex-lifestyle" rel="nofollow">nice link</a> | <a href="http://lunaticmandrakes.tumblr.com" rel="nofollow">superb 8</a> <a href="http://ymnaivepor1974.posterous.com/prospect-a-beautiful-lovemaking-life" rel="nofollow">look 6</a> | <a href="http://darlingcelebs.tumblr.com" rel="nofollow">check link</a> | <a href="http://epsysubqui1989.posterous.com/impotence-problems-problems-in-addition-to-so" rel="nofollow"> do not forget link</a> <a href="http://tripaserdeu1976.posterous.com/cool-tadalafil-extremely-question-substance" rel="nofollow"> also check</a> | <a href="http://numteriro1982.posterous.com/business-lead-a-pleasant-lovemaking-lifestyle" rel="nofollow">check check</a>Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-15575652.post-39452989849240466222007-03-07T02:55:00.000+08:002007-03-07T02:55:00.000+08:00This quote below is from the following website, e...This quote below is from the following website, essays written by an English GP Malcolm Kendrick<BR/><BR/>http://www.thincs.org/Malcolm.htm<BR/><BR/>" I suppose that most people believe that it must have been proven by now that blood pressure lowering does reduce the rate of CHD, rendering the example of a high temperature somewhat pointless. Well, I am going to quote you quite a long passage from the European Heart Journal, issue 20, October 2000. Please read it carefully, for it is actually quite stunning.<BR/><BR/>‘It is widely believed that randomised trials have proved that lowering blood pressure is beneficial. Actually, that is not true. All antihypertensive drugs have profound effects on the cardiovascular system, aside from their haemodynamic (blood pressure lowering) effect. How much, if any, of the observed risk reduction can be ascribed to the reduction in pressure and how much to the direct action of the drug on the cardiovascular system? Motivated by the belief in the linear relationship of risk to pressure, many automatically attribute the risk reduction to the pressure reduction, ignoring the direct action of the drugs on the target outcomes. But results of a multitude of clinical trials make it clear that such a simplistic view cannot be true. In fact, evidence is mounting (especially from the newer trials) that it is the direct effects that are producing most, if not all, or the benefit and that the accompanying blood pressure reduction may be just an inconsequential side effect.’ Port S et al.<BR/><BR/>In short, there is no evidence whatsoever that lowering blood pressure has any effect on CHD.<BR/><BR/><BR/><BR/>I suppose that most people believe that it must have been proven by now that blood pressure lowering does reduce the rate of CHD, rendering the example of a high temperature somewhat pointless. Well, I am going to quote you quite a long passage from the European Heart Journal, issue 20, October 2000. Please read it carefully, for it is actually quite stunning.<BR/><BR/>‘It is widely believed that randomised trials have proved that lowering blood pressure is beneficial. Actually, that is not true. All antihypertensive drugs have profound effects on the cardiovascular system, aside from their haemodynamic (blood pressure lowering) effect. How much, if any, of the observed risk reduction can be ascribed to the reduction in pressure and how much to the direct action of the drug on the cardiovascular system? Motivated by the belief in the linear relationship of risk to pressure, many automatically attribute the risk reduction to the pressure reduction, ignoring the direct action of the drugs on the target outcomes. But results of a multitude of clinical trials make it clear that such a simplistic view cannot be true. In fact, evidence is mounting (especially from the newer trials) that it is the direct effects that are producing most, if not all, or the benefit and that the accompanying blood pressure reduction may be just an inconsequential side effect.’ Port S et al.<BR/><BR/>In short, there is no evidence whatsoever that lowering blood pressure has any effect on CHD.<BR/><BR/><BR/><BR/>I suppose that most people believe that it must have been proven by now that blood pressure lowering does reduce the rate of CHD, rendering the example of a high temperature somewhat pointless. Well, I am going to quote you quite a long passage from the European Heart Journal, issue 20, October 2000. Please read it carefully, for it is actually quite stunning.<BR/><BR/>‘It is widely believed that randomised trials have proved that lowering blood pressure is beneficial. Actually, that is not true. All antihypertensive drugs have profound effects on the cardiovascular system, aside from their haemodynamic (blood pressure lowering) effect. How much, if any, of the observed risk reduction can be ascribed to the reduction in pressure and how much to the direct action of the drug on the cardiovascular system? Motivated by the belief in the linear relationship of risk to pressure, many automatically attribute the risk reduction to the pressure reduction, ignoring the direct action of the drugs on the target outcomes. But results of a multitude of clinical trials make it clear that such a simplistic view cannot be true. In fact, evidence is mounting (especially from the newer trials) that it is the direct effects that are producing most, if not all, or the benefit and that the accompanying blood pressure reduction may be just an inconsequential side effect.’ Port S et al.<BR/><BR/>In short, there is no evidence whatsoever that lowering blood pressure has any effect on CHD."Anonymousnoreply@blogger.com